RFA for Fibroids Linked to Higher Treatment Failure Than Myomectomy
A prospective multicenter study (ULTRA trial) compared laparoscopic radiofrequency ablation (RFA) and laparoscopic myomectomy for symptomatic uterine leiomyomata, tracking subsequent procedures and composite failure within 2 years. The study reported surgical failure in 15.2% of RFA patients versus 3.8% of myomectomy patients (adjusted OR 4.17), and composite failure in 46.4% versus 25.5% (adjusted OR 3.18), with submucosal and lateral leiomyomata associated with higher odds of RFA failure.