CGM Metrics Linked to Cardiovascular Risk Beyond Fasting Glucose, HbA1c
This cross-sectional analysis from the Framingham Heart Study examined continuous glucose monitoring (CGM) data from 1,356 participants without diabetes or cardiovascular disease who wore a blinded Dexcom G6 Pro CGM for up to 10 days. The study reported that CGM measures, such as time spent above 140 mg/dL, were associated with higher 10-year cardiovascular disease risk estimates and higher odds of hypertension and dyslipidemia, even after adjusting for fasting plasma glucose. The authors noted that CGM-defined glycemic profiles often diverged from traditional prediabetes classifications based on fasting glucose and HbA1c, and that profiles reflecting higher dysglycemia were linked to elevated cardiovascular risk estimates and worse cardiometabolic risk factors.
Most relevant for: Adults without diagnosed diabetes or cardiovascular disease being evaluated for cardiometabolic risk, including those with normal or borderline fasting glucose and HbA1c results.
Read the original at Diabetes CareSummary written by an AI model from the source text and dated by the source's publication date. Check the original before acting on it. How MedFollow selects and summarizes updates.
Informational only. Not medical advice. Not a substitute for clinical judgment. Always consult current guidelines and your own clinical judgment.
Specialties
More endocrinology updates
- 2025 ATA thyroglobulin cutoff may miss recurrences in higher-risk DTCOct 13, 2026
- ADA-EASD 2026 consensus favors earlier SGLT2/GLP-1 use in type 2 diabetesOct 2, 2026
- Lean MASLD shows milder liver histology but similar clinical outcomesSep 30, 2026
- Oral GLP-1 agonist orforglipron shows cardiovascular non-inferiority to insulin glargineSep 30, 2026
- Retatrutide Trial Shows Weight Loss and Comorbidity Benefits in ObesitySep 29, 2026