Case Report: Recurrent Pleural Effusion With Weight Loss in Older Man

This case report describes a 72-year-old man with coronary artery disease, heart failure with preserved ejection fraction, smoldering multiple myeloma, treated latent TB, and Agent Orange exposure who presented with dyspnea, 10-lb weight loss, and recurrent exudative pleural effusion. The report states that pleural fluid cytology and culture were negative, CT imaging showed diffuse mesenteric and retroperitoneal lymphadenopathy with mild PET activity but no cervical or thoracic nodal involvement, and that thoracentesis performed one week before admission followed a prior thoracentesis four months earlier, suggesting accelerated fluid reaccumulation.

Most relevant for: Older adults with multiple comorbidities presenting with recurrent exudative pleural effusion of unclear etiology.

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