Cystoid Macular Edema Found in Quarter of Eyes After Corneal Cell Injection

A multicenter retrospective cohort study of 57 eyes that underwent cultured human corneal endothelial cell injection therapy for corneal endothelial disease found cystoid macular edema (CME) in 15 eyes (26.3%) postoperatively. The study reported that preoperative prostaglandin analog use, glaucoma, topical glaucoma medication use, and worse preoperative visual acuity were significantly associated with CME detection, with edema occurring predominantly early after surgery. All cases resolved with topical NSAIDs or sub-Tenon triamcinolone, and the study found no significant difference in 6-month visual acuity between eyes with and without CME.

Most relevant for: Patients undergoing cultured corneal endothelial cell injection therapy, particularly those with glaucoma or prior prostaglandin analog use.

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