Case report: cystic lung disease with progressive renal failure resists treatment

This case report describes a 50-year-old woman with a two-year history of productive cough and low-grade fever who was found to have diffuse cystic lung lesions with bilateral nodules and calcifications on CT, without a definitive diagnosis on prior bronchoscopy and biopsy. She subsequently developed rising creatinine (peaking at 5.21 mg/dL) and renal hypertension, with a renal biopsy suggesting acute interstitial nephritis; a three-month course of methylprednisolone did not improve either her chest imaging or renal function.

Most relevant for: Relevant to evaluation of patients with unexplained diffuse cystic lung disease accompanied by progressive renal impairment.

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