Review Summarizes Diagnosis and Treatment of Idiopathic NPH
This review describes idiopathic normal pressure hydrocephalus (iNPH), a disorder affecting 1% to 4% of adults 65 and older and 6% to 8% of those over 80, characterized by gait disturbance, urinary dysfunction, and cognitive decline. The review states that diagnosis relies on clinical findings plus neuroimaging showing ventricular enlargement, and that large-volume lumbar puncture or extended lumbar drainage can help predict shunt responsiveness. The authors report that after shunt placement, 75% to 80% of patients show gait improvement, with cognitive and urinary improvement in 50% to 70%, while shunt complications including overdrainage, underdrainage, malfunction, and infection also occur.
Most relevant for: Older adults being evaluated for gait, urinary, or cognitive symptoms suggestive of normal pressure hydrocephalus.
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