Vitamin A deficiency varies by bariatric procedure, meta-analysis finds

A systematic review and meta-analysis of 21 studies examined biochemical vitamin A deficiency and ocular manifestations following bariatric surgery. Pooled prevalence ranged from 18.0% after Roux-en-Y gastric bypass to 59.0% after biliopancreatic diversion, with pregnancy-specific prevalence after RYGB reaching 63.3%; ocular presentation occurred at a median of 5 years after RYGB versus 14 to 27 years after other procedures, and 93% of treated cases improved or resolved. The authors note certainty was limited by study heterogeneity, small subgroup sizes, and selective outcome reporting.

Most relevant for: Patients who have undergone bariatric surgery, particularly those who are pregnant or presenting with night blindness, ocular surface disease, or unexplained visual decline years after the procedure.

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