TIA linked to sustained long-term increase in dementia risk

A population-wide matched cohort study using linked administrative health data from Ontario, Canada (2002-2022) examined dementia risk after TIA in over 113,000 patients compared with matched population controls and stroke patients. The study reported dementia in 19.3% of TIA patients over a mean follow-up of 7.11 years, with dementia risk highest in the first year (HR 1.75) and remaining elevated over 20 years (overall HR 1.34) compared with controls; risk converged with that of stroke patients after 5 years. The authors state dementia occurred far more frequently than incident stroke after TIA, highlighting cognitive decline as a major long-term complication.

Most relevant for: Patients who have experienced a transient ischemic attack, particularly regarding long-term cognitive outcomes and follow-up care.

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