ResearchSource: Neurology

Review Outlines Evolving Diagnosis and Treatment of Cerebral Venous Thrombosis

This review discusses cerebral venous thrombosis (CVT), an uncommon cerebrovascular disorder predominantly affecting young adults and women. It reports that anticoagulation remains the cornerstone of treatment, with emerging evidence supporting direct oral anticoagulants as safe and effective alternatives to vitamin K antagonists in selected patients, while endovascular therapy is limited to select cases of deterioration despite medical therapy and decompressive surgery may be lifesaving in severe cases with large lesions. The review notes that long-term outcomes extend beyond functional recovery, with many patients experiencing persistent cognitive symptoms, fatigue, and reduced quality of life, and identifies gaps in managing severe CVT and in early prognostic stratification.

Most relevant for: Patients diagnosed with cerebral venous thrombosis, particularly young adults and women, and those requiring long-term anticoagulation or secondary prevention.

Read the original at Neurology

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