Stroke recurrence after artery dissection clusters early, linked to morphology

A multicenter South Korean registry study (CRCS-K-NIH, 2011-2021) analyzed 711 patients with craniocervical artery dissection diagnosed within 7 days of acute ischemic stroke or TIA to characterize the timing and predictors of recurrent stroke. The study reported that recurrence was 8.7% by day 1, 17.4% within a week, and 19.9% at one year, with incidence dropping sharply after the first week; dissection location was not associated with recurrence, but stenosis without dilatation and double lumen sign were independently associated with higher one-year recurrence, with double lumen specifically linked to recurrence in the 2-3 day window. The authors state these findings support morphology-based, time-specific risk characterization, while noting limitations from the retrospective design and East Asian-only population.

Most relevant for: Young adults with craniocervical artery dissection presenting with acute ischemic stroke or TIA, particularly in the hyperacute post-diagnosis period.

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