Centralized retinoblastoma program achieves high survival, eye-salvage rates
A retrospective cohort study reviewed 601 children (1000 affected eyes) with retinoblastoma treated over two decades at a centralized multidisciplinary center in Jordan that used telemedicine and an international twinning partnership, drawing referrals from 15 countries. The study reported an overall eye salvage rate of 61% (74.4% among conservatively treated eyes, ranging from 98% in Group A to 17% in Group E), metastasis in 4.3% and secondary malignancy in 1.2% of patients at median 120-month follow-up, and 5-year overall survival of 96%. The authors concluded that this centralized model achieved survival and globe-preservation outcomes comparable to high-income settings despite resource constraints.
Most relevant for: Clinicians managing retinoblastoma in resource-limited settings, including those involved in referral, globe-salvage decision-making, or multidisciplinary retinoblastoma care networks.
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