Fasciectomy and collagenase show similar outcomes in recurrent Dupuytren contracture

A single-center randomized controlled trial compared surgical fasciectomy and collagenase injection in 59 patients with recurrent Dupuytren contracture. The trial reported no statistically significant differences between groups in extension deficit improvement or re-recurrence rate at 2 years, though the fasciectomy group had more severe adverse events (one digital nerve and two digital artery lacerations) and greater short-term worsening in QuickDASH scores.

Most relevant for: Patients with recurrent Dupuytren contracture being considered for surgical fasciectomy or collagenase injection.

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