Larger ADM-to-implant surface ratio linked to lower capsular contracture risk

A retrospective cohort study of 730 breasts undergoing immediate prepectoral wrap-around implant-based reconstruction with smooth implants examined the relationship between acellular dermal matrix (ADM) surface area relative to implant surface area and capsular contracture (CC). The study reported that a higher ADM-to-implant surface area ratio was associated with lower odds of Baker grade III-IV CC, while radiotherapy remained the strongest risk factor, increasing CC odds 4.10-fold. CC occurred in 7.4% of non-irradiated and 23.8% of irradiated breasts over the first two years after surgery.

Most relevant for: Patients undergoing immediate prepectoral implant-based breast reconstruction with ADM wrap-around technique, including those receiving radiotherapy.

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