Real-world PTAB patency rates lower than in DETOUR trials

A retrospective single health-system analysis of 49 percutaneous transmural arterial bypass (PTAB) procedures in 44 patients treated for long-segment femoropopliteal occlusions found primary patency rates of 47.6% at 12 months and 8.3% at 18 months, lower than the 72-81% and higher rates reported in the DETOUR1 and DETOUR2 trials at 1 year. The study reported 16 stent occlusions, 20 patients requiring reintervention, and 2 major amputations secondary to stent occlusion; all patients had achieved technical success and were discharged on combined antiplatelet and anticoagulant therapy. The authors state these findings underscore the need for close postprocedural surveillance and timely reintervention in patients undergoing PTAB.

Most relevant for: Patients with long-segment superficial femoral or popliteal artery occlusions being considered for or having undergone percutaneous transmural arterial bypass.

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