Nebulized TXA cut surgery rates in pediatric posttonsillectomy bleeding

A retrospective study at a tertiary children's hospital evaluated a treatment algorithm using nebulized tranexamic acid (TXA) for posttonsillectomy hemorrhage in patients under 18 presenting to the emergency department. The study reported that among patients with small clots (under 50% of the tonsillar fossa), surgery was needed in 21% of TXA-treated patients versus 88% of untreated historical controls, with no adverse events reported with TXA use. The authors estimated the protocol avoided 32 surgeries and reduced costs by approximately $138,162 over the study period.

Most relevant for: Pediatric patients presenting to the emergency department with posttonsillectomy hemorrhage, particularly those with clots covering less than half of the tonsillar fossa.

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