Longer Migraine Duration Before Surgery Linked to Worse Outcomes

A retrospective cohort study of 54 patients undergoing migraine trigger-site surgery in Taiwan (2019-2024) found that longer time from migraine onset to surgery was independently associated with higher postoperative headache frequency, alongside preoperative frequency. Patients operated on at or before the cohort median of 15 years from onset had a 96% success rate (≥50% frequency reduction) and 43% complete elimination, compared with 77% success and 15% elimination in those with longer disease duration before surgery. The study reports each additional year of disease duration was associated with 0.34 more headache days per month postoperatively.

Most relevant for: Patients with medically refractory migraine being considered for trigger-site surgery.

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