Lower FFR-CT values linked to higher risk of MI and death

A nationwide cohort study of 7836 patients across 27 England sites who underwent coronary CT angiography with FFR-CT analysis for stable coronary artery disease examined associations between FFR-CT measurements and 3-year cardiovascular outcomes. The study reported that lower FFR-CT values were associated with incrementally greater risk of myocardial infarction, cardiovascular death, all-cause death, and revascularization, independent of cardiovascular risk factors and stenosis severity, and identified 0.67 as the optimal cutoff for predicting future cardiovascular events. The study also reported that adding FFR-CT improved risk discrimination compared with a model based on risk factors and stenosis severity alone.

Most relevant for: Patients with stable coronary artery disease undergoing coronary CT angiography with FFR-CT evaluation.

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