Clinical factors linked to bloodstream and urinary infections in gastroschisis

A retrospective analysis of 3987 infants with gastroschisis across 47 NICUs in the Children's Hospitals Neonatal Database (2010-23) examined predictors of bloodstream infection (BSI) and urinary tract infection (UTI). The study reported early BSI in 0.4%, any BSI in 7.6%, and UTI in 3.5% of infants, with bowel atresia, silo/staged closure, patch closure, and additional anomalies independently associated with these infections. The authors state these identified predictors could help distinguish lower-risk patients from those more likely to develop infection.

Most relevant for: Neonates with gastroschisis managed in the NICU, particularly those with bowel atresia, staged or patch closure, or additional congenital anomalies.

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