Meta-analysis finds 31% recurrence after sinus surgery for AFRS
A systematic review and meta-analysis of 31 studies (1474 patients) examined outcomes of endoscopic sinus surgery (ESS) for allergic fungal rhinosinusitis. The pooled analysis reported a disease recurrence rate of 31% and a surgical revision rate of 19%, alongside a mean SNOT-22 score reduction of 23.37 points indicating improved sinonasal quality of life. The authors reported that postoperative oral itraconazole use was not associated with lower recurrence or revision rates, and called for further studies to define optimal postoperative adjuvant therapy.
Most relevant for: Patients with allergic fungal rhinosinusitis undergoing or being considered for endoscopic sinus surgery.
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