Meta-analysis finds sialendoscopy effective for RAI-induced sialadenitis

A systematic review and meta-analysis pooled data from 22 studies encompassing 387 patients and 626 salivary glands treated with sialendoscopy for radioactive iodine-induced sialadenitis. The most common intraoperative findings were ductal stenosis and mucous plugs; 87.9% of patients and 71.2% of glands showed partial to complete symptomatic improvement, with a pooled recurrence rate of 7.4% and no major complications reported. The authors conclude that sialendoscopy is an effective, minimally invasive treatment for this condition with low recurrence and minimal morbidity.

Most relevant for: Patients with salivary gland dysfunction following radioactive iodine therapy, such as those treated for thyroid cancer.

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