Review highlights gaps in ACS guidance for Kawasaki disease patients

This review article synthesizes current evidence on acute coronary syndrome (ACS) occurring in patients with a history of Kawasaki disease (KD), covering epidemiology, pathophysiology of coronary artery aneurysms, interventional imaging, revascularization, antithrombotic therapy, and post-ACS surveillance. The authors state that ACS remains underrecognized in KD and that existing ACS guidelines are derived from atherosclerotic disease, which does not adequately address the distinctive mechanisms, anatomy, and thrombosis risk seen in KD. The review notes that management requires collaboration between pediatric and adult cardiologists as the population at risk grows into adulthood.

Most relevant for: Patients with a history of Kawasaki disease and coronary artery aneurysms who present with acute coronary syndrome, spanning pediatric to adult care settings.

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Informational only. Not medical advice. Not a substitute for clinical judgment. Always consult current guidelines and your own clinical judgment.