Therapeutic CPAP Levels Correlate With Airway Collapsibility on DISE-PAP

A retrospective cohort study of 94 adults with obstructive sleep apnea who underwent Drug-Induced Sleep Endoscopy with Positive Airway Pressure (DISE-PAP) examined the relationship between therapeutic CPAP levels and pharyngeal opening pressure (PhOP), a measure of upper airway collapsibility. The study reported a positive correlation between median CPAP, CPAP at 95% of use time, and PhOP, with PhOP consistently lower than both CPAP measures; BMI and AHI showed only mild correlations with CPAP, and the AHI-PhOP association did not reach statistical significance. The authors state these findings may allow surgeons to estimate upper airway collapsibility from therapeutic CPAP levels when DISE-PAP is unavailable.

Most relevant for: Patients with obstructive sleep apnea being evaluated for upper airway surgical interventions using PAP data in place of direct DISE-PAP testing.

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